Complete laparoscopic management of locally recurrent renal cell carcinoma after radical nephrectomy

Abstract

Objective: Description of the laparoscopic approach for local recurrence of renal cell carcinoma after radical nephrectomy and oncological outcomes.

Study design: A retrospective cohort analysis.

Materials and methods: A retrospective cohort analysis included patients who underwent laparoscopic resection for RCC recurrence at XXX. The laparoscopic technique utilized either transabdominal or retroperitoneal approaches. The primary outcome measure was disease-free survival. Secondary outcome measures included operative time, estimated blood loss, and complications.

Results: Thirteen patients underwent laparoscopic resection, with a mean operative time of 189 minutes and low complication rates. Pathological reports confirmed clear-cell RCC in the majority of cases. The median time to recurrence post-nephrectomy was 67 months, with a 3-year disease-free survival rate of 85%. All patients had negative margins, and at the last follow-up all patients were alive.

Limitations: The limitations of this study include its small sample size and retrospective design.

Value: The full laparoscopic approach for patients with local recurrence of renal cell carcinoma.

Conclusion: Laparoscopic resection of locally recurrent RCC post-radical nephrectomy appears to be safe and effective, demonstrating promising oncological outcomes. Larger prospective studies are warranted to validate these findings and establish standardized guidelines for widespread implementation.